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Klonopin (Clonazepam) is a benzodiazepine derivative that has an anticonvulsant, anxiolytic, muscular-relaxing, amnestic, sedative, and hypnotic effect. It reduces the excitability of the subcortical areas of the brain (limbic system, thalamus, and hypothalamus) and disturbs their interaction with the cortex. It oppresses polysynaptic spinal reflexes. It is quickly and completely absorbed in the digestive tract. After taken orally, Cmax is achieved in 1-2 hours. It is excreted mainly in urine. 1 tablet contains 0.5 or 2 mg of Clonazepam; one blister contains 30 pcs, one pack contains 1 blister.
Ataxia, discoordination, fatigue, drowsiness, weakness, dizziness, impaired memory and speech, visual disturbances, nervousness, weakening of the ability to learn, emotional lability, decreased libido, confusion, depression, symptoms of catarrhal inflammation of the upper respiratory tract, hypersalivation, constipation, abdominal pain, loss of appetite, muscle pain, menstrual disorders, urinary frequency, erythromycin, leukopenia and thrombocytopenia, increased blood concentrations of transaminases and alkaline phosphatase, paradoxical reactions - excitement, cutaneous allergic manifestations, insomnia (it requires drug withdrawal).
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Klonopin / Clonazepam should be taken according to the doctor's prescription. It is up to your doctor to determine the dose of Klonopin / Clonazepam indicated for you and the duration of therapy. Do not change the prescribed dosage on your own initiative. If you think that the action of the medicine is too weak or too strong, talk to your doctor or pharmacist. To avoid side effects at the start of therapy, the doctor will gradually increase the daily dose until the required maintenance dose is reached. Generally the dosage for adults is as follows: starting dose: 1.5 mg / day (one light orange 0.5 mg tablet 3 times a day). Within the first three weeks of treatment, your doctor will increase the dose to 4-8 mg / day (in rare cases up to 20 mg / day). The total daily dose can be taken in a single dose in the evening. However, the doctor may consider it appropriate to divide the daily dose into several administrations during the day. In elderly patients, the physician should prescribe the lowest possible dose and dose escalation should be done with caution. To facilitate dosage adjustment, Klonopin / Clonazepam 0.5 mg tablets can be halved. Klonopin / Clonazepam 2 mg tablets can be halved or divided into four parts to facilitate dosage adjustment.
Klonopin / Clonazepam treatment should never be stopped abruptly. With regard to epileptic children and infants, the doctor will in any case decide whether Klonopin / Clonazepam therapy is suitable. For children and infants, 0.5 mg light orange tablets or drops are indicated. Take Klonopin / Clonazepam tablets with a glass of water or a non-alcoholic drink. Never drip Klonopin / Clonazepam drops directly into the mouth. After each opening of the bottle, make sure that the dropper is firmly inserted into the neck of the bottle. The drops are administered with a spoon, mixed with water, tea or orange juice.
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